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Section12:Cell Proliferation Assays

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The measurement of cell proliferation, viability and activation are key areas in a wide variety of cell biological approaches and enables researchers to:

  • Optimize cell culture conditions,
  • Quantitate the activity of growth factors and cytokines,
  • Facilitate the discovery of new therapeutic agents such as anti-cancer agents,
  • Assess the efficacy of therapeutic agents such as anti-cancer agents,
  • Assess the toxicity of environmental pollutants,
  • Assess compound-mediated toxicity

The need for sensitive, reliable, rapid and easy methods has led to the development of several standard assays.