Section5:Additional Resources

From Assay Guidance Wiki

Web sites:

• GraphPad Prism (http://www.graphpad.com/www/welcome.html)
• Curvefit.com - related to GraphPad Prism web site (http://www.curvefit.com/index.htm)
• GE Healthcare (Formerly Amersham Biosciences) (http://www.amershambiosciences.com/)
• Perkin Elmer Life and Analytical Sciences (http://las.perkinelmer.com/)
• Receptor Binding Tutorial (http://www.unmc.edu/Pharmacology/receptortutorial/home.htm)

Suggested Reading - General Receptor Binding:

• Textbook of Receptor Pharmacology. (2003). Second Edition. Foreman, J.C. and Johansen, T., Editors. CRC Press, New York.
• Kenakin, T. (1997): Pharmacologic Analysis of Drug-Receptor Interaction. Lippincott-Raven Publishers, Philadelphia.
• Receptor Binding Techniques. (1999). Methods in Molecular Biology Series, Volume 106, Keen, M., Editor. Humana Press, New Jersey.
• The Pharmacology of Functional, Biochemical, and Recombinant Receptor Systems. (2000). Handbook of Experimental Biology, Volume 148, Kenakin, T and Angus, J.A., Editors. Springer-Verlag, New York.
• Receptor-Ligand Interactions: A Practical Approach. (1992). The Practical Approach Series. E.C. Hulme, Editor. Oxford University Press, New York.
• Receptor Biochemistry: A Practical Approach. (1990). The Practical Approach Series. E.C. Hulme, Editor. Oxford University Press, New York.
• Motulsky, H.J. Analyzing Data with GraphPad Prism. (1999). GraphPad Software, San Diego, CA. Available at: http://www.graphpad.com/manuals/analyzingdata.pdf
• Limbird, L.E. Cell Surface Receptors: A Short Course on Theory and Methods. (1996). Kluwer Academic Publishers, Boston.
• Winzor, D.J. and Sawyer, W.H. Quantitative Characterization of Ligand Binding. (1995). Wiley-Liss, Inc., New York.
• Lutz, M. W., Menius, J. A., Choi, T. D., Gooding-Laskody, R., Domanico, P. L., Goetz, A. S. and Saussy, D. L. (1996) Experimental design for high-throughput screening. Drug Discovery Today 1(7): 277-286.
• Kahl, S. D., Hubbard, F. R., Sittampalam, G. S. and Zock, J. M. (1997) Validation of a High Throughput Scintillation Proximity Assay for 5-Hydroxytryptamine1E Receptor Binding Activity. J. Biomol. Screen. 2(1): 33-39.
• Sun, S., Almaden, J., Carlson, T.J., Barker, J. and Gehring, M.R. (2005). Assay development and data analysis of receptor-ligand binding based on scintillation proximity assay. Metab Eng. 7:38-44.

Suggested Reading - Fluorescence Polarization:

• Cantor and Schimmel in Biophysical Chemistry Part II: Techniques for the study of biological structure and function. pp. 454-465. (1980).
• Huang, X., Fluorescence polarization competition assay: The range of resolvable inhibitor potency is limited by the affinity of the fluorescent ligand. J. Biomol. Screening, 2003;8:34-38
• Kenakin, TP (1993) in Pharmacologic analysis of drug/receptor interaction, 2nd ed., New York:Raven p. 483.
• Munson PJ and Rodbard, D: An exact correction to the “Cheng-Prusoff” correction. J. Receptor. Res. 1988;533-546
• Roehrl MHA, Wang JY, Wagner G. A General Framework for Development and Data Analysis of Competitive High-Throughput Screens for Small-Molecule Inhibitors of Protein-Protein Interactions by Fluorescence. 2004; Biochemistry; 43 (51):16056 -16066, 2004
• Roehrl MHA, Wang JY, Wagner G. Discovery of Small-Molecule Inhibitors of the NFAT-Calcineurin Interaction by Competitive High-Throughput Fluorescence Polarization Screening. 2004; Biochemistry;43(51):16067 -16075, 2004.
• Turconi S, Shea K, Ashman S, Fantom K, Earnshaw DL, Bingham RP, Haupts UM, Brown MJB, Pope A: Real experiences of uHTS: A prototypic 1536-well fluorescence anisotropy-based uHTS screen and application of well-level quality control procedures. 2001; J. Biolmol. Screening 6:275-290
• Lin, S, Bock, CL, Gardner, DB, Webster, JC, Favata, MF, Trzaskos, JM, Oldenburg, KR A high-throughput fluorescent polarization assay for nuclear receptor binding utilizing crude receptor extract. 2002, Anal Biochem. 300:15-21
• Lee, PH and Bevis, DJ Development of a homogeneous high throughput fluorescence polarization assay for G protein-coupled receptor binding. 2000, J. Biomol. Screening. 5:415-419
• Banks, P and Harvey, M Considerations for using fluorescence polarization in the screening of g protein-coupled receptors. 2002, J Biomol Screen. 7:111-7
• Do, EU, Choi, G, Shin, J, Jung, W-S and Kim, S-I Fluorescence polarization assays for high-throughput screening of neuropeptide FF receptors. 2004 Anal. Biochem. 330:156-163
• Allen, M, Reeves, J and Mellor, G. High throughput fluorescence polarization: A homogeneous alternative to radioligand binding for cell surface receptors. 2000, J. Biomol. Screen. 5:63-69
• Burke, TJ, Loniello, KR, Beebe, JA and Ervin, KM Development and application of fluorescence polarization assays in drug discovery. 2003, Combinatorial Chemistry & High Throughput Screening. 6:183-194
• Beasely, J.R., Dunn, DA, Walker, TL, Parlato, SM, Lehrach, JM and Auld, DS. (2003) Evaluation of compound interference in immobilized metal ion affinity-based fluorescence polarization detection with a four million member compound collection. Assays and Drug Development Technologies.1, 455-459.

Also see: http://www.invitrogen.com/downloads/FP8.pdf